Sea fennel and mushrooms in skincare: why Prep is retinol-free

If Prep doesn't have retinol, what's doing the work on texture? A salt-loving coastal plant and two mushrooms.

Sea fennel and mushrooms in skincare: why Prep is retinol-free

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Cōpḍī is hormone-informed skincare: skin longevity science for sensitive skin that keeps changing.

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People ask us all the time: if Prep doesn't have retinol, what's doing the work on texture?

The short answer is a complex made from sea fennel and two mushrooms, shiitake and turkey tail. Here's what they are, what the science says, and why we built Prep without retinol.

Why no retinol

Retinoids have more clinical evidence behind them than almost anything in skincare. We're not going to pretend otherwise.

But they come with a ramp-up: weeks of dryness, peeling and sensitivity while skin adjusts. For skin in hormonal change, which is often already drier, thinner and more reactive, that adjustment period can be the hardest part. We wanted a first step that works with your skin from the first day. So Prep is retinol-free, with no ramp-up.

That doesn't make sea fennel "plant retinol." It isn't, and no one has shown it works the same way. It's a different ingredient doing a different job.

Sea fennel: a plant that lives on salt

Crithmum maritimum, also called rock samphire, grows on sea cliffs and rocky shores, in salt spray and full sun. It's a halophyte, a plant built to survive salty soil.1 Plants that live under that kind of stress tend to be rich in protective compounds, and sea fennel is no exception: it's full of phenolics, mainly chlorogenic acid, which show strong antioxidant activity in lab tests.2

The renewal research is early and all in the lab. In one 2025 study, a chlorogenic-acid-rich sea fennel extract helped a lab-grown skin model rebuild its outer layer after UV stress.3 A 2025 review of 79 studies on the plant concluded that studies in living systems are still limited.4

So we describe it for what it does in a formula: Prep smooths the look of texture.

Mushrooms: shiitake and turkey tail

Mushrooms are on the table most days in both our homes, and they're in Prep for a reason of their own: antioxidant defense.

  • Shiitake extract showed antioxidant activity in a 2026 lab study, and it was gentle on human skin cells.5
  • Turkey tail extract protected skin cells from free-radical damage in the lab.6

A 2024 review of 52 studies on mushroom extracts and skin cells found antioxidant and moisturizing activity across many species.7 Again, that's lab work, not human trials.

Are adaptogenic mushrooms a real thing in skincare?

Not really. "Adaptogen" describes something you ingest that helps your body cope with stress.8 Europe's medicines regulator has said the term isn't accepted in pharmacology.9 It has no defined meaning for something you put on your skin, so we don't use it.

What's true is simpler: sea fennel and these mushrooms come from organisms that cope with harsh environments, and they're rich in antioxidants. In Prep, that's part of the antioxidant pillar of our hormone-informed philosophy.

And snow mushroom?

Snow mushroom (Tremella fuciformis) is in Prep too, but for hydration, not texture. Its polysaccharide is a water-loving sugar chain that forms a light, hydrating film.10 In Prep it's layered with five molecular weights of hyaluronic acid and polyglutamic acid.

You may have read that snow mushroom "holds 500 times its weight in water." We looked for the source and couldn't find one in the research, so we don't say it.

 

With care,
Afsheen & Samantha

FAQ

What does sea fennel do in skincare?

Sea fennel (Crithmum maritimum) is a coastal plant rich in phenolic antioxidants such as chlorogenic acid. In Prep, as part of a complex with shiitake and turkey tail, it smooths the look of texture.

Is sea fennel a retinol alternative?

No. Prep is retinol-free, but sea fennel is a different ingredient doing a different job, and no study has shown it works the way retinol does.

Are adaptogenic mushrooms real in skincare?

Not really. "Adaptogen" describes something you ingest that helps the body cope with stress, and Europe's medicines regulator has said the term is not accepted in pharmacology. We describe these mushrooms by what they bring: antioxidants.

Can I use sea fennel on sensitive skin?

Prep is made for reactive skin and has no added fragrance. Sea fennel is in the same plant family as celery and fennel, so if you react to those, check with your doctor and patch-test first.

This article is for general information and isn't medical advice. For concerns about your skin or health, talk to your doctor or dermatologist.

Sources

  1. Giannakoula AE et al. Mitigation of oxidative damage caused by salinity in the halophyte Crithmum maritimum L. via biostimulant-enhanced antioxidant activity. Plants (Basel), 2025. PMID 41470670.
  2. Lemoine C et al. A characterization of biological activities and bioactive phenolics from the non-volatile fraction of the edible and medicinal halophyte sea fennel. Foods, 2024;13(9):1294. PMID 38731664.
  3. Huang H et al. Full-component extract of Crithmum maritimum and its effect on epidermal regeneration. RSC Advances, 2025. PMID 39835209.
  4. Dzhoglova V et al. Crithmum maritimum L.: phytochemical profile, biological activities, and therapeutic potential. Molecules, 2025;30(13):2832. PMID 40649346.
  5. Kucuk SD, Jabet P, Groso A et al. Cosmeceutical and dermatological potential of shiitake mushroom (Lentinula edodes) extract. Journal of Cosmetic Dermatology, 2026;25(2):e70724. PMID 41656649.
  6. Chou CH et al. Enzymatic hydrolysates obtained from Trametes versicolor polysaccharopeptides protect human skin keratinocytes against AAPH-induced oxidative stress and inflammation. Journal of Cosmetic Dermatology, 2019. PMID 31033173.
  7. Paterska M et al. Macrofungal extracts as a source of bioactive compounds for cosmetical anti-aging therapy: a comprehensive review. Nutrients, 2024;16(16):2810. PMID 39203946.
  8. Panossian AG et al. Evolution of the adaptogenic concept from traditional use to medical systems. Medicinal Research Reviews, 2021. PMID 33103257.
  9. European Medicines Agency, HMPC. Reflection paper on the adaptogenic concept. EMEA/HMPC/102655/2007, 8 May 2008. Link
  10. Galla R et al. Non-animal hyaluronic acid from Tremella fuciformis. Foods, 2025;14(8):1362. PMID 40282763.